Safety
Safety information
Know these symptoms before you start. If you have any of them, get help right away.
Symptoms that need help right away
Call 911 or go to an emergency room
- Trouble breathing, swelling of the face, lips, tongue, or throat.
- Chest pain, fainting, or a racing heartbeat with dizziness.
- Severe abdominal pain that does not go away, especially with vomiting or pain radiating to the back.
- Any thought of harming yourself.
Get medical advice today
- Vomiting that will not stop, or no fluids kept down for 12 hours.
- Yellowing of the skin or eyes, dark urine, or pale stools.
- Very little urine for a day, or confusion.
- A lump in the neck, hoarseness that does not go away, or trouble swallowing.
- Blood sugar under 70 with symptoms, in a patient on diabetes medication.
- Sudden vision changes, in a patient with diabetes.
- A positive pregnancy test.
- A severe rash, blistering, or widespread hives.
DR. FOOD patients: message your care team in the app right away. A physician reviews these the same day.
Who shouldn't take GLP-1 medication
- You or a close family member have had medullary thyroid cancer, or you have MEN 2.
- You're pregnant, breastfeeding, or planning a pregnancy.
- You have type 1 diabetes.
- You have an active eating disorder.
- You've had a serious allergic reaction to a GLP-1 medication.
Your clinician reviews your full health history before prescribing, including conditions not listed here.
Common side effects
The most common are nausea, constipation, diarrhea, vomiting, fatigue, and headache. Most are stomach-related and worst in the first week after a dose change.
Your care team helps you manage them, and your dose only goes up when a check-in shows you're ready.
Medication details
These summaries aren't complete. Read the full prescribing information for every warning and instruction.
For Wegovy, the Wegovy pill, and Foundayo, your clinician goes over the full prescribing information with you at your visit.
Zepbound®
tirzepatide injection
FDA-approved for chronic weight management in eligible adults when paired with reduced-calorie nutrition and increased physical activity.
- Boxed warning: thyroid C-cell tumors observed in rats.
- Do not use with personal/family history of medullary thyroid carcinoma (MTC) or with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- Serious side effects may include pancreatitis, gallbladder problems, acute kidney injury, severe gastrointestinal reactions, and severe allergic reactions.